The course physical pharmacy is designed to provide the students with a wide background in pharmacy related physical principles essential for their study in pharmaceutics in succeeding years. Physical pharmacy integrates basic knowledge of mathematics, physics and chemistry. The course aims at introducing important pharmacy-related physical principles in areas such as states of matter, phase equilibrium and phase rule, solutions, adsorption, solubility, buffers and isotonic solutions and dispersions. It also focuses on the theories behind the phenomena needed for dosage form design. The course also presents basic understanding of types of disperse systems and methods of their preparation and assessment.
COURSE LEARNING OUTCOMES (CLO)
CLO: 1. To describe the fundamentals of pharmacy profession, different physicochemical processes, their purpose, method, techniques and importance in physical pharmacy.
CLO: 2. To illustrate principles and steps for different pharmaceutical systems, their purpose, components, special requirements and applications relevant to pharmacy.
CLO: 3. To apply knowledge of basic concepts of physical pharmacy to different physiochemical processes and pharmaceutical systems
- PHARMACY ORIENTATION:
- Introduction and orientation to the Profession of Pharmacy in relation to Hospital Pharmacy, Retail Pharmacy, Industrial Pharmacy, Forensic Pharmacy, Pharmaceutical education and research etc.
- HISTORY AND LITERATURE OF PHARMACY:
- A survey of the history of pharmacy through ancient Greek and Arab periods with special reference to contribution of Muslim scientists to pharmacy and allied sciences. An introduction of various official books.
- PHYSICO-CHEMICAL PRINCIPLES:
- _Introduction, types, concentration expressions, ideal and real solution, colligative properties, their mathematical derivations and applications in pharmacy, molecular weight determinations, distribution co-efficient and its applications in pharmacy_
- _Factors affecting solubility, Surfactants, their properties and types. Micelles
- _Techniques and processes of adsorption in detail_
- _pH, pH indicators, pka, buffers, buffer’s equation, isotonic solutions and their applications in pharmacy. Hydrolysis_ Types and protection of drugs against hydrolysis_
- _Particle size, shapes and distribution of particles, Methods of determination of particle size and importance of particle size in Pharmacy_
- _Types, methods of preparation, properties (optional, kinetic, electrical). Dialysis and artificial kidney, stability of colloids, protectionand sensitization phenomenon and application of colloids in Pharmacy_
- _Types, theories of emulsification, emulsifying agents their classification and stability of emulsion_
- _Type, Methods of Preparation, Properties, Suspending agents, their classification and stability_