[vc_row el_class=”inner-body-content” css=”.vc_custom_1667462582637{padding-top: 30px !important;padding-bottom: 20px !important;}”][vc_column][vc_custom_heading text=”COURSE OBJECTIVES” use_theme_fonts=”yes” css=”.vc_custom_1667462567226{margin-top: 0px !important;}”][vc_column_text]The purpose of this course is to explain basic concepts and principles of biopharmaceutics and pharmacokinetics. The necessary initial handling procedure of animals (rabbit, mice, rats) is briefly demonstrated. Blood sampling techniques will also discussed under this course. In-vitro studies regarding time dependent dissolution is also included in this course. The necessary mathematical expressions needed to estimate the serum concentration of different drugs, bioavailability studies and pharmacokinetic parameters will also discuss along with compartmental model.[/vc_column_text][vc_custom_heading text=”COURSE LEARNING OUTCOMES (CLO)” font_container=”tag:h3|text_align:left” use_theme_fonts=”yes”][vc_column_text]CLO: 1. To describe the general procedures used for the handling and blood sampling of animals.
CLO: 2. To illustrate methodologies and mathematical approaches for the estimation of pharmacokinetic parameters.
CLO: 3. To apply knowledge of biopharmaceutics in different compartmental models and multiple dosing regimen.
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1. NOTE: Practical of the subject shall be designed from time to time on the basis of the above-mentioned theoretical topics and availability of the facilities, e.g. Blood Sampling Techniques (In Laboratory Animals like dog, rabbits, mice etc. in human beings), In-vitro dissolution studies, Optional dose determination, Measurement of rate of Bioavailability, Determination of relative and absolute bioavailability. Plasma level-time curve (Determination of Pharmacokinetic parameters). Determination of plasma protein binding. Urinary sampling techniques in laboratory animals. Renal excretion of drugs or drug disposition in animals and humans.

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